Nyob rau xyoo tas los no, qhov teeb meem rog thoob ntiaj teb tau dhau los ua qhov hnyav zuj zus. Raws li "Global Obesity Atlas 2025" uas tau tshaj tawm los ntawm World Obesity Federation, tag nrho cov neeg laus rog thoob ntiaj teb yuav nce ntxiv los ntawm 524 lab hauv xyoo 2010 mus rau 1.13 billion hauv xyoo 2030, nce ntxiv ntau dua 115%. Nyob rau hauv qhov teeb meem no, ntau tus neeg siv khoom tab tom nrhiav cov khoom xyaw ntuj uas tuaj yeem pab tiv thaiv kev rog. Thaum Lub Rau Hli xyoo no, kev tshawb fawb luam tawm hauv phau ntawv xov xwm "npj science of food" tau taw qhia tias curcumin tau txo cov rog visceral hauv MASH nas los ntawm kev txwv tsis pub tso tawm ntawm gastric inhibitory polypeptides (GIP) los ntawm hypoxic intestinal raug mob. Qhov kev tshawb pom no tsis yog tsuas yog muab cov tswv yim tshiab rau kev tiv thaiv kev rog xwb tab sis kuj nthuav dav kev lag luam ntawm curcumin.
Curcumin tiv thaiv kev sib sau ua ke ntawm cov rog hauv plab li cas? Kev sib sau ua ke ntawm cov rog hauv plab yog hais txog kev sib sau ua ke ntawm cov rog tsis zoo lossis ntau dhau. Kev noj zaub mov uas muaj carbohydrate ntau, cov rog ntau thiab tsis tawm dag zog tuaj yeem ua rau lub zog tsis sib npaug, ua rau cov rog hauv plab ntau dhau. Txoj hnyuv plab yog qhov tseem ceeb rau kev nqus cov rog. Kev sib sau ua ke ntawm cov rog hauv plab yog ib qho tseem ceeb ntawm kev ua haujlwm tsis zoo ntawm cov kab mob steatohepatitis (MASH). Raws li kev tshawb fawb, ob qho tib si curcumin thiab tshuaj tua kab mob tuaj yeem txo qhov hnyav ntawm cov nas MASH, thiab curcumin thiab tshuaj tua kab mob muaj cov txiaj ntsig zoo.
Kev tshawb fawb txog lub tshuab pom tau tias curcumin feem ntau txo qhov hnyav ntawm cov rog hauv plab, tshwj xeeb tshaj yog nyob rau hauv cov ntaub so ntswg perirenal. Curcumin tiv thaiv qhov hnyav nce los ntawm kev txwv tsis pub tso tawm ntawm GIP thiab txo cov ntaub so ntswg adipose nyob ib puag ncig lub raum. Curcumin ua rau txo qis hauv plab hnyuv GIP tso tawm txwv tsis pub ua haujlwm ntawm GIP receptors, yog li txo cov adipogenesis thiab o ntawm cov ntaub so ntswg adipose perirenal. Tsis tas li ntawd, curcumin tuaj yeem txo cov hnyuv me me hypoxia los ntawm kev tiv thaiv cov hnyuv epithelium thiab cov hlab ntsha barrier, yog li txo qhov tso tawm ntawm GIP. Hauv kev xaus, cov nyhuv pharmacological ntawm curcumin rau cov rog hauv plab feem ntau ua rau tsis muaj zog ntawm kev tso tawm ntawm GIP los ntawm kev txwv tsis pub hypoxia los ntawm kev cuam tshuam ntawm plab hnyuv.
Curcumin, tus "kws tshaj lij tiv thaiv kev o," feem ntau yog los ntawm cov hauv paus hniav thiab rhizomes ntawm Curcuma (Curcuma longa L.). Nws yog ib qho tshuaj polyphenolic uas tsis muaj molecular thiab feem ntau yog siv ua seasoning hauv ntau yam khoom noj. Xyoo 1815, Vegel et al. thawj zaug tshaj tawm txog kev rho tawm ntawm "cov khoom daj txiv kab ntxwv" los ntawm rhizome ntawm turmeric thiab hu ua curcumin. Nws tsis yog txog xyoo 1910 uas Kazimierz thiab lwm tus kws tshawb fawb tau txiav txim siab nws cov qauv tshuaj lom neeg kom yog diferulic acylmethane. Cov pov thawj uas twb muaj lawm qhia tau hais tias curcumin muaj cov nyhuv tiv thaiv kev o. Nws tuaj yeem ua rau nws cov nyhuv tiv thaiv kev o los ntawm kev txwv tsis pub Toll-like receptor 4 (TLR4) txoj kev thiab nws txoj kev downstream nuclear factor kB (NF-kB) signaling txoj kev, thiab txo cov khoom tsim tawm ntawm cov yam ntxwv pro-inflammatory xws li interleukin-1 β (IL-1β) thiab tumor necrosis factor -α (TNF-α). Lub caij no, nws cov khoom tiv thaiv kev o yog suav tias yog lub hauv paus ntawm ntau yam kev ua ub no ntawm lub cev, thiab ntau qhov kev tshawb fawb ua ntej lossis kev tshawb fawb hauv tsev kho mob tau tshawb nrhiav nws cov txiaj ntsig hauv cov kab mob o. Ntawm lawv, kab mob plab hnyuv, mob pob qij txha, mob psoriasis, kev nyuaj siab, atherosclerosis thiab COVID-19 yog cov chaw tshawb fawb kub tam sim no.
Nrog rau kev loj hlob ntawm kev ua lag luam niaj hnub no, curcumin nyuaj rau kom tau txais txiaj ntsig zoo los ntawm kev noj zaub mov ib leeg xwb thiab yuav tsum tau noj cov tshuaj ntxiv. Yog li ntawd, nws tau loj hlob ntau hauv kev lag luam khoom noj khoom haus thiab cov tshuaj ntxiv.
Justgood Health kuj tau tsim ntau yam curcumin gummy supplements thiab curcumin capsules. Muaj ntau tus neeg faib khoom tau tuaj kho kom haum rau lawv cov koob tshuaj lossis cov duab tshwj xeeb ntawm lawv lub npe.
Kev tshawb fawb ntxiv txog cov txiaj ntsig ntawm curcumin tau pom tias curcumin tsis yog tsuas yog pab tiv thaiv kev rog dhau xwb tab sis kuj muaj ntau yam xws li kev tiv thaiv kev laus, kev tiv thaiv neuro, kev pab txo qhov mob pob txha thiab kev txhawb nqa rau kev noj qab haus huv ntawm lub plawv. Antioxidant: Kev tshawb fawb tau pom tias curcumin tuaj yeem tshem tawm cov dawb radicals ncaj qha thiab txhim kho kev ua haujlwm mitochondrial los ntawm kev ua kom cov kab ke xws li silencing regulatory protein 3 (SIRT3), yog li txo qhov kev tsim cov tshuaj reactive oxygen ntau dhau (ROS) los ntawm qhov chaw thiab ua kom zoo rau kev puas tsuaj ntawm cov hlwb oxidative. Neuroprotection: Cov pov thawj tshawb fawb uas twb muaj lawm qhia tau hais tias kev o tuaj yeem cuam tshuam nrog kev nyuaj siab. Curcumin tuaj yeem txhim kho cov tsos mob ntawm kev nyuaj siab thiab kev ntxhov siab ntawm cov neeg mob uas muaj kev nyuaj siab. Curcumin tuaj yeem pab tiv thaiv kev puas tsuaj ntawm neuronal los ntawm interleukin-1 β (IL-1β) thiab lwm yam, thiab txo cov cwj pwm zoo li kev nyuaj siab los ntawm kev ntxhov siab ntev. Yog li ntawd, nws yuav ua lub luag haujlwm zoo hauv kev txhawb nqa kev noj qab haus huv ntawm lub hlwb thiab kev tswj hwm kev xav. Kev txo qhov mob ntawm cov leeg nqaij thiab pob txha: Kev tshawb fawb tau qhia tias curcumin tuaj yeem txhim kho cov tsos mob ntawm cov tsiaj mob pob qij txha thiab tiv thaiv cov pob qij txha thiab cov leeg nqaij los ntawm kev txo qhov o. Curcumin tuaj yeem txo qhov mob ntawm cov leeg nqaij thiab pob txha vim nws tuaj yeem tiv thaiv kev tso tawm ntawm cov yam ntxwv pro-inflammatory xws li tumor necrosis factor -α (TNF-α) thiab interleukin-1 β (IL-1β), txo cov lus teb o hauv zos, thiab yog li txo cov tsos mob ntawm cov pob qij txha o thiab mob. Txhawb kev noj qab haus huv ntawm cov hlab ntsha: Hais txog lub plawv, curcumin tuaj yeem ua haujlwm los ntawm kev tswj cov lipids hauv cov ntshav, txo cov roj cholesterol tag nrho hauv cov ntshav, triglycerides thiab cov roj cholesterol lipoprotein qis, thaum nce cov roj cholesterol lipoprotein siab. Tsis tas li ntawd, curcumin kuj tseem tuaj yeem tiv thaiv kev loj hlob ntawm cov leeg nqaij ntawm cov hlab ntsha thiab cov lus teb o, uas yog pab tau rau kev tiv thaiv kev tshwm sim thiab kev loj hlob ntawm cov kab mob plawv xws li atherosclerosis.
Lub sijhawm tshaj tawm: Lub Ib Hlis-08-2026